Case report describes diabetic myonecrosis with no nephropathy, highlighting diagnostic and treatment challenges.
Diabetic myonecrosis (also known as diabetic muscle infarction, or DMI) is a rare complication of poorly controlled diabetes, with fewer than 200 discrete cases reported in the English language medical literature over the past 60 years. In most published cases, diabetic myonecrosis occurs concurrently with other micro/macrovascular diabetic sequelae (e.g., nephropathy). Here, we describe a case of a patient with DMI without nephropathy, whose presentation was otherwise pathognomonic for DMI. We share this case to increase clinician awareness of this uncommon condition and to highlight the diagnostic and treatment considerations to keep in mind when managing suspected DMI, as choice of treatment can dramatically affect clinical course.
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Shapiro et al. (2026) studied this question.
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