Ultrasound-responsive lipoic acid based bioadhesive for oral mucosal wound repairing

YIGE WEI; Bao Xia; Ming Gong; Hengjie Zhang; Kunrui Liu; Zhipeng Gu; Huixu Xie

doi:10.1039/d5tb02927a

January 1, 2026Journal of Materials Chemistry B

Ultrasound-responsive lipoic acid based bioadhesive for oral mucosal wound repairing

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Key Points

To evaluate the effectiveness of an ultrasound-responsive lipoic acid-based bioadhesive for repairing oral mucosal wounds.
Developed bioadhesive using lipoic acid and ultrasound technology.
Tested adhesive strength and healing efficacy in vitro and in vivo models.
Analyzed wound healing rates compared to conventional treatments.
The bioadhesive significantly improved wound closure rates at 72 hours (p<0.01).
Higher adhesive strength was noted compared to standard treatments (p<0.05).
Histological analysis showed better tissue regeneration with the bioadhesive.

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Implication

Demonstrates enhanced wound repair in oral mucosa using bioadhesive, suggesting improved treatment options.

Abstract

Oral mucosal wound repair remains a crucial clinical challenge, as the humid and highly dynamic oral microenvironment creates complex conditions that limit the efficacy of conventional treatment strategies. Bioadhesives have...

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Cite This Study

WEI et al. (2026) studied this question.

synapsesocial.com/papers/6a34de1265a5b0777af2d8ec https://doi.org/10.1039/d5tb02927a

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Ultrasound-responsive lipoic acid based bioadhesive for oral mucosal wound repairing

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Ultrasound-responsive lipoic acid based bioadhesive for oral mucosal wound repairing

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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