Reveals early detection of cutaneous amyloidosis improves outcomes in patients with multiple myeloma, suggesting urgency in diagnosis.
Symmetric, purpuric hand nodules and macroglossia prompted skin biopsy revealing immunoglobulin light chain amyloidosis, leading to the diagnosis of multiple myeloma. Early detection of typical and atypical cutaneous amyloidosis presentations, such as this patient, is imperative for clinicians to initiate timely hematologic workup and treatment to improve patient outcomes and survival.
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Lyon et al. (2026) studied this question.
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