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June 19, 2026Journal of Clinical MedicineOpen Access

Anterior Midline Skull Base Meningiomas: A Systematic Review of Resection Rates, Functional Outcomes, and Perioperative Complications Following Contemporary Endoscopic Endonasal Versus Transcranial Approaches

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Authors

USUmid SulaimanovUniversity of Wisconsin–MadisonIUIrem UsluUniversity of Wisconsin–MadisonOAOmar AlomariSağlık Bilimleri Üniversitesi

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Implication

Systematic review compares endoscopic and transcranial approaches for meningiomas, suggesting tailored strategies for optimal outcomes.

Key Points

  • This review assesses the effectiveness and outcomes of endoscopic endonasal and transcranial approaches for anterior midline skull base meningiomas.
  • Systematic review following PRISMA guidelines.
  • Included 35 studies with 1866 patients published between January 2010 and August 2025.
  • Outcomes were compared based on tumor subtype for EEA and TCA.
  • Gross total resection rates exceeded 90% for both approaches.
  • EEA showed superior visual improvement in TS/PS meningiomas with optic canal involvement.
  • TCA resulted in better olfactory preservation in OGMs, with a decline in cerebrospinal fluid leak rates due to NSF reconstruction.

Cite This Study

Sulaimanov et al. (2026) studied this question.

synapsesocial.com/papers/6a34de4165a5b0777af2da68https://doi.org/10.3390/jcm15124676
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