Burden and Outcomes of Sepsis Using Phoenix Criteria: Single-Center Cohort Study in a South African PICU, 2024

Ashleigh T. Sent; Shamiel Salie; Brenda Morrow

doi:10.1097/pcc.0000000000003993

June 17, 2026Pediatric Critical Care MedicineOpen Access

Burden and Outcomes of Sepsis Using Phoenix Criteria: Single-Center Cohort Study in a South African PICU, 2024

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Key Points

This study aims to characterize the burden and outcomes of pediatric sepsis using Phoenix criteria and evaluate the Phoenix Sepsis Score's effectiveness in predicting mortality and length of stay.
Retrospective cohort study conducted in a single PICU setting
332 pediatric emergency admissions included based on specific sepsis criteria
No interventions were applied; data on admissions were analyzed for mortality and length of stay.
41.3% of patients had sepsis, with 30.4% experiencing septic shock
Each one-point increase in the Phoenix Sepsis Score doubled the odds of mortality (2.21 odds ratio, p < 0.001)
The score showed strong discriminatory capacity for mortality, with an area under the curve of 0.894.

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Implication

Single-center cohort study reveals high mortality and length of stay associated with pediatric sepsis in a PICU, indicating critical need for improved risk assessment.

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Cite This Study

Sent et al. (2026) studied this question.

synapsesocial.com/papers/6a34dec865a5b0777af2e176 https://doi.org/10.1097/pcc.0000000000003993

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Burden and Outcomes of Sepsis Using Phoenix Criteria: Single-Center Cohort Study in a South African PICU, 2024

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Burden and Outcomes of Sepsis Using Phoenix Criteria: Single-Center Cohort Study in a South African PICU, 2024

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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