Clone-Fiber Organ Genesis (CFOG): Patient-Specific iPS-Derived Clonal Cells Guided by Bioconductive Piezoelectric Fiber Networks for Autonomous Organ Construction

Organ transplantation faces two fundamental problems: donor shortage and rejection. This paper proposes Clone-Fiber Organ Genesis (CFOG), a design concept that reduces both to zero. Materials: patient-specific iPS-derived clonal cells (zero rejection — self-origin). Blueprint: bioconductive piezoelectric fiber networks (SIBM design — cells come autonomously). Organ-specific fiber network designs are proposed for: Heart — helical fiber orientation implementing ECCE five-layer electromagnetic engine; Liver — hexagonal lattice fiber network replicating hepatic lobule structure; Kidney — glomerular loop fiber configuration enabling autonomous filtration membrane formation; Spinal cord — linear axial fiber bridges reconnecting severed neural ends (theoretical paralysis recovery); Skin — parallel/cross fiber mesh replicating dermal collagen architecture for large-area wound coverage. The ten-stage autonomous construction process: cell harvest → iPS initialization → fiber network fabrication → placement → cell seeding → FICI triple stimulation (mechano/electrical/adhesion) → SIBM encapsulation → GMFT Qi-mesh current activation → autonomous organ function onset → full somatic integration. This paper is the sixth and integrative layer of a unified invention series: ECCE (10.5281/zenodo.20725907), CPMH (10.5281/zenodo.20725945), SIBM (10.5281/zenodo.20726036), GMFT (10.5281/zenodo.20726125), FICI (10.5281/zenodo.20726159), CFOG (this paper). V = N / D theoretical basis: fiber network density (N) encodes organ design information; surgical intervention (D) approaches zero; patient cells (N) follow fiber blueprint autonomously. CFOG represents the full biological realization of V = N / D. Published as open knowledge base. To regenerative medicine researchers: design the fiber, grow the clone, combine them. The organ will emerge. Do not wait for donors.