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June 19, 2026Journal of Bronchology & Interventional PulmonologyOpen Access

Definitive Pleural Interventions and Survival in Malignant Pleural Effusion

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Authors

PFPedro Magalhães FerreiraIPO PortoDCD Pinto CoelhoUniversidade do PortoCFCláudia FreitasUniversidade do Porto

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Implication

Retrospective cohort study evaluates survival benefits of definitive pleural interventions in malignant pleural effusion, indicating significant prognostic value.

Key Points

  • The aim is to determine the survival impact of various definitive pleural interventions in patients with malignant pleural effusion.
  • Retrospective cohort study of 783 patients with malignant pleural effusion from 2012 to 2022.
  • Interventions included medical thoracoscopy, chest tube drainage, and indwelling pleural catheters.
  • Data on mortality and relapse rates were analyzed using multivariate regression.
  • Overall mortality was high at 89.8%, with a median survival of 172 days, significantly different among interventions (P<0.001).
  • Successful pleurodesis resulted in more than three times higher postpleurodesis survival (P<0.001).
  • The overall relapse rate was 52.8%, with a median time to relapse of 29 days, differing significantly between treatment modalities (P<0.001).

Cite This Study

Ferreira et al. (2026) studied this question.

synapsesocial.com/papers/6a34dff765a5b0777af2ef70https://doi.org/10.1097/lbr.0000000000001074
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