Key result
Coronary revascularization, particularly coronary artery bypass grafting, provides additional prognostic benefits over medical therapy alone in patients with left ventricular systolic dysfunction.
Why the study?
The effects of coronary revascularization in patients with LVSD are not well studied, and decisions regarding revascularization, timing, ischemia assessment, and viability remain challenging and debatable.
Does coronary revascularization improve clinical outcomes in patients with left ventricle systolic dysfunction?
Does coronary revascularization improve clinical outcomes in patients with left ventricle systolic dysfunction?
This review highlights that surgical revascularization provides a survival benefit over medical therapy and PCI in patients with ischemic left ventricular systolic dysfunction, though contemporary randomized trials for PCI are still needed.
Viability testing in LVSD revascularization remains debatable; leaves open optimal selection and timing.
The effects of coronary revascularization in patients with left ventricle systolic dysfunction (LVSD) are not well studied. The decision about revascularization and its timing remain challenging, not only related to procedural risk, but also linked to other several limitations including assessment of ischemia, viability, and ability to predict LV recovery. The role of viability as a prognostic marker for patients with LVSD and its use as a therapeutic target remains debatable. In this article, we will review the role of LVSD in patients undergoing coronary revascularization alongside the role of ischemia and viability assessment. We will provide a review of the literature on the outcomes of coronary revascularization, both surgically and percutaneously, in patients with LVSD.
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Abdalwahab et al. (2022) conducted a review in Left ventricular systolic dysfunction and coronary artery disease. Coronary revascularization (CABG and PCI) vs. Medical therapy was evaluated. Coronary revascularization, particularly coronary artery bypass grafting, provides additional prognostic benefits over medical therapy alone in patients with left ventricular systolic dysfunction.
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