What is the clinical evidence from this study?

Study design: Case Report. Population: Massive mitral annular calcification (n=1). Intervention: Multimodality and longitudinal imaging.

What does this research mean for the field?

Serial multimodality imaging effectively tracks the structural progression of massive mitral annular calcification and characterizes its extent and associated valvular dysfunction over time. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To describe a case of massive mitral annular calcification and its diagnostic significance.

June 19, 2026Radiology Case ReportsOpen Access

Massive mitral annular calcification with valvular involvement: Multimodality and longitudinal imaging correlation

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Key result

Serial multimodality imaging demonstrates 8-year progression of massive MAC in a patient with exertional dyspnea.

Why the study?

Mitral annular calcification rarely evolves into a massive form with relevant diagnostic and clinical implications.

Key Points

To describe a case of massive mitral annular calcification and its diagnostic significance.
Patient underwent serial imaging over 8 years, including chest radiography, echocardiography, and cardiac CT.
Echocardiography assessed valve function and structural changes.
Computed tomography provided detailed characterization of the calcification.
Significant calcification of the mitral and aortic valve apparatus was observed.
Echocardiography indicated preserved left ventricular systolic function with mild to moderate regurgitation.
Cardiac CT revealed massive, high-attenuation calcification with crescentic morphology at the mitral annulus.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 76-year-old woman with a history of transient ischemic attacks and prior syncopal episodes presenting with progressive exertional dyspnea, followed over 8 years.

Exposure

Longitudinal and multimodality imaging (chest radiography, transthoracic echocardiography, and cardiac computed tomography)

Outcome

Characterization of massive mitral annular calcification

Longitudinal and multimodality imaging, particularly cardiac computed tomography, is highly valuable for definitively characterizing massive mitral annular calcification.

Discussion

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Implication

May inform serial CT monitoring of MAC; leaves open prospective validation of multimodality protocols.

Cite This Study

Montatore et al. (2026) conducted a case report in Massive mitral annular calcification (n=1). Multimodality and longitudinal imaging was evaluated. Serial multimodality imaging over 8 years demonstrated the progression of massive mitral annular calcification in a 76-year-old woman with exertional dyspnea.

synapsesocial.com/papers/6a35982fdd3be7785e70ed57 https://doi.org/10.1016/j.radcr.2026.05.087

Topics

Mitral valve intervention Echocardiography

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Massive mitral annular calcification with valvular involvement: Multimodality and longitudinal imaging correlation

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Topics

Massive mitral annular calcification with valvular involvement: Multimodality and longitudinal imaging correlation

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider