What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Successful repair of coarctation of the aorta (n=105). Intervention: Gothic geometry of the aortic arch vs. Crenel and normal geometry. Primary outcome: Hypertension (p=<0.001).

What does this research mean for the field?

Gothic geometry of the aortic arch is independently associated with resting hypertension and increased left ventricular mass index in patients following successful repair of aortic coarctation. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To explore how the shape of the aortic arch influences blood pressure after repair of coarctation of the aorta.

June 19, 2026European Heart Journal

Late systemic hypertension and aortic arch geometry after successful repair of coarctation of the aorta

Q: What are the key findings of this study?

Gothic geometry of the aortic arch was associated with a significantly higher rate of resting hypertension compared to crenel and normal geometries (45.5% vs 27.8% and 4.6%, P<0.001).

Q: What does this research mean for the field?

Gothic geometry of the aortic arch is independently associated with resting hypertension and increased left ventricular mass index in patients following successful repair of aortic coarctation. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Q: What question did this study set out to answer?

To explore how the shape of the aortic arch influences blood pressure after repair of coarctation of the aorta.

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Key result

Gothic aortic arch geometry is linked to a ~10-fold higher rate of resting hypertension.

P<0.001
n=105

Key Points

To explore how the shape of the aortic arch influences blood pressure after repair of coarctation of the aorta.
Analyzed data from 105 patients aged 15.3±6 years with previous coarctation repair.
Categorized aortic arch shapes into gothic, crenel, and normal.
Measured blood pressure and utilized MRI to assess aortic arch metrics.
Hypertension observed in 25.7% of patients; highest rate (45.5%) in gothic arch geometry.
Resting systolic BP and left ventricular mass index significantly elevated in patients with gothic arch.
Only the A/T ratio and gothic geometry correlated with hypertension and elevated blood pressure levels.

Study Design

Type

Cross-Sectional (n=105)

Structured PICO

Population

105 patients (mean age 15.3 years) with successful repair of aortic coarctation who underwent MRI and blood pressure measurements.

Outcome

Resting hypertensionsurrogate

Main Result

Absolute Event Rate: 45.5% vs 4.6%

p-value: p=<0.001

Discussion

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Implication

Gothic geometry of the aortic arch is strongly associated with resting hypertension and higher left ventricular mass index in patients after successful repair of aortic coarctation.

Cite This Study

Ou et al. (2004) conducted a cross-sectional in Successful repair of coarctation of the aorta (n=105). Gothic geometry of the aortic arch vs. Crenel and normal geometry was evaluated on Hypertension (p=<0.001). Gothic geometry of the aortic arch was associated with a significantly higher rate of resting hypertension compared to crenel and normal geometries (45.5% vs 27.8% and 4.6%, P<0.001).

synapsesocial.com/papers/6a35b2487f329793c62de3cd https://doi.org/10.1016/j.ehj.2004.07.021

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Implication

Gothic geometry of the aortic arch is strongly associated with resting hypertension and higher left ventricular mass index in patients after successful repair of aortic coarctation.

Late systemic hypertension and aortic arch geometry after successful repair of coarctation of the aorta

Key Points

Study Design

Structured PICO

Main Result

Discussion

Implication

Cite This Study

Late systemic hypertension and aortic arch geometry after successful repair of coarctation of the aorta

Key Points

Study Design

Structured PICO

Main Result

Discussion

Implication

Cite This Study

Also Consider

Also Consider