Key result
Acute preload reduction from hemodialysis significantly decreased 3-dimensional principal strain from -38.10% to -35.33% (p < 0.001), demonstrating that 3D strain parameters are volume-dependent.
Why the study?
Does acute preload reduction via hemodialysis affect 3-dimensional echocardiographic deformation parameters in patients with end-stage renal disease?
Population
58 patients with end-stage renal disease regularly undergoing hemodialysis, mean age 59 ± 12 years, 50%…
Comparison
Hemodialysis causing acute preload reduction vs Pre-hemodialysis baseline state
Design
Cohort, Echocardiographer was blinded to the study design
Follow-up
immediately before and less than 30 min after a single…
Authors
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3D strain parameters warrant caution in volume-altered patients; leaves open their incremental value beyond 2D measures in ESRD.
Observational (n=58)
Single-blind
No
Does acute preload reduction via hemodialysis affect 3-dimensional echocardiographic deformation parameters in patients with end-stage renal disease?
Absolute Event Rate: -35.33% vs -38.1%
p-value: p=<0.001
Three-dimensional echocardiographic strain parameters, including principal strain, twist, and torsion, are significantly affected by acute preload reduction and should be interpreted with caution regarding patient volume status.
Ahn et al. (2017) conducted an observational in End-stage renal disease (ESRD) (n=58). Hemodialysis (acute preload reduction) vs. Pre-hemodialysis state was evaluated on 3-dimensional principal strain (PS) (p=<0.001). Acute preload reduction from hemodialysis significantly decreased 3-dimensional principal strain from -38.10% to -35.33% (p < 0.001), demonstrating that 3D strain parameters are volume-dependent.
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