What question did this study set out to answer?

The study aims to assess the incidence of permanent pacemaker (PPM) necessity within 30 days following CoreValve transcatheter aortic valve implantation.

February 22, 2011CirculationOpen Access

Permanent Pacemaker Insertion After CoreValve Transcatheter Aortic Valve Implantation

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Population

243 patients without preexisting permanent pacemakers undergoing CoreValve transcatheter aortic valve…

Design

Cohort

Follow-up

30 days

Authors

MKMuhammed Zeeshan KhawajaKing's College London RRRonak RajaniCardiac Imaging ACAndrew C. CookUniversity College London

Discussion

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Implication

High PPM rates after CoreValve TAVI warrant close AV block monitoring; leaves open identification of modifiable risks in prospective studies.

Key Points

The study aims to assess the incidence of permanent pacemaker (PPM) necessity within 30 days following CoreValve transcatheter aortic valve implantation.
Examined data from 270 patients across 10 UK centers.
Analyzed pre-existing ECG abnormalities and outcomes following implantation.
Conducted multivariable analysis on factors associated with PPM requirement.
81 patients (33.3%) required PPM insertion within 30 days.
Prolonged QRS duration increased from 105±23 ms to 135±29 ms (P<0.01).
Atrioventricular block showed an odds ratio of 6.29 (95% CI, 3.55 to 11.15) for requiring PPM.

Structured PICO

Population

243 patients without preexisting permanent pacemakers undergoing CoreValve transcatheter aortic valve implantation, mean age 81.3±6.7 years, 50.6% male, from 10 centers in the United Kingdom.

Intervention

CoreValve transcatheter aortic valve implantation

Outcome

Incidence of permanent pacing within 30 days of CoreValve implantationsafety

One third of patients undergoing CoreValve TAVI require a permanent pacemaker within 30 days, with risk driven by periprocedural AV block, balloon predilatation, larger prosthesis size, increased septal diameter, and prolonged QRS.

Cite This Study

Khawaja et al. (2011) studied this question.

synapsesocial.com/papers/6a35da79a4e90ae4d3ef5045 https://doi.org/10.1161/circulationaha.109.927152

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Implication

High PPM rates after CoreValve TAVI warrant close AV block monitoring; leaves open identification of modifiable risks in prospective studies.

Permanent Pacemaker Insertion After CoreValve Transcatheter Aortic Valve Implantation

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Permanent Pacemaker Insertion After CoreValve Transcatheter Aortic Valve Implantation

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Also Consider