Key result
Dietary supplementation with 5% young persimmon fruit for 10 weeks significantly lowered plasma chylomicron, VLDL, LDL cholesterols, and triglycerides in apolipoprotein E-deficient mice.
Why the study?
Does young persimmon fruit supplementation reduce plasma lipids in ApoE-deficient mice?
Population
Male C57BL/6.KOR-ApoEshl mice (n=5)
Design
Preclinical
Follow-up
10 weeks
Authors
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Hypothesis-generating in ApoE-deficient mice; leaves open any role in human lipid management pending clinical trials.
Does young persimmon fruit supplementation reduce plasma lipids in ApoE-deficient mice?
Young persimmon fruit supplementation lowers plasma lipids in ApoE-deficient mice, likely by accelerating fecal bile acid excretion.
Matsumoto et al. (2008) studied Hyperlipidemia (Apolipoprotein E-deficiency) (n=5). Young persimmon fruit (YP) was evaluated on Plasma chylomicron, VLDL, LDL cholesterols, and triglyceride levels. Dietary supplementation with 5% young persimmon fruit for 10 weeks significantly lowered plasma chylomicron, VLDL, LDL cholesterols, and triglycerides in apolipoprotein E-deficient mice.
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