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September 6, 2020Virus ResearchOpen Access

Classical swine fever virus: the past, present and future

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Why the study?

Classical swine fever persists in certain areas and re-emerges regularly despite strict control policies, necessitating an updated overview of advances in research, diagnostics, and vaccines.

Design

Review

Authors

LGLlilianne GangesUniversitat Autònoma de BarcelonaHCHelen CrookeAnimal and Plant Health AgencyJBJosé Alejandro BohórquezThe University of Texas Health Science Center at Tyler

Discussion

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Implication

May inform swine disease control in endemic zones; leaves open needs for updated eradication models and vaccine research.

Key Points

  • The aim is to summarize the existing knowledge of classical swine fever virus (CSFV) and recent advancements in research.
  • Review of established knowledge and recent advances in CSFV research, diagnostics, and vaccine development.
  • Analysis of genetic diversity and implications for pestivirus taxonomy.
  • Discussion on disease pathogenesis, immunity, and virus-host interactions.
  • CSF persists in specific regions despite control efforts, with significant economic implications.
  • Recent findings reveal critical insights into the genetic diversity and virulence determinants of CSFV.
  • Challenges remain in developing effective diagnostic tools and modern serologically compatible vaccines.

Structured PICO

P
Population
Swine affected by Classical swine fever virus (CSFV)

Provides a comprehensive overview of recent advances in classical swine fever virus research, including genetic diversity, pathogenesis, diagnostics, and vaccine development.

Cite This Study

Ganges et al. (2020) studied this question.

synapsesocial.com/papers/6a35db42e8fad655376e508fhttps://doi.org/10.1016/j.virusres.2020.198151
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