Key result
Multimodality imaging, including echocardiography, cardiac magnetic resonance, and FDG-PET, provides complementary clinical information essential for the diagnosis, management, and prognostication of cardiac sarcoidosis.
Why the study?
Cardiac sarcoidosis is an increasingly recognized cause of heart failure and arrhythmia that has been historically challenging to identify, but diagnosis has improved with advanced imaging.
Multimodality imaging using echocardiography, CMR, and FDG-PET is essential for the comprehensive diagnosis, risk stratification, and longitudinal management of cardiac sarcoidosis.
Enhanced imaging aids CS detection; leaves open standardized multimodal protocols for screening and management.
Cardiac sarcoidosis (CS) is an increasingly recognized cause of heart failure and arrhythmia. Historically challenging to identify, particularly in the absence of extracardiac sarcoidosis, diagnosis of CS has improved with advancements in cardiac imaging. Recognition as well as management may require interpretation of multiple imaging modalities. Echocardiography may serve as an initial screening study for cardiac involvement in patients with systemic sarcoidosis. Cardiac magnetic resonance imaging (CMR) provides information on diagnosis as well as risk stratification, particularly for ventricular arrhythmia in the setting of late gadolinium enhancement. More recently, 18 F-fluorodeoxyglucose position emission tomography (FDG-PET) has assumed a valuable role in the diagnosis and longitudinal management of patients with CS, allowing for the assessment of response to treatment. Hybrid FDG-PET/CT may also be used in the evaluation of extracardiac inflammation, permitting the identification of biopsy sites for diagnostic confirmation. Herein we examine the approach to diagnosis and management of CS using multimodality imaging via a case-based review.
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Wand et al. (2022) conducted a review in Cardiac Sarcoidosis. Multimodality imaging (Echocardiography, CMR, FDG-PET) was evaluated. Multimodality imaging, including echocardiography, cardiac magnetic resonance, and FDG-PET, provides complementary clinical information essential for the diagnosis, management, and prognostication of cardiac sarcoidosis.
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