What does this research mean for the field?

Erythropoietin (EPO) possesses pleiotropic effects beyond erythropoiesis, offering substantial therapeutic potential for tissue engineering, regenerative medicine, organoid development, and immune modulation, provided delivery and bioactivity challenges can be overcome. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This review aims to investigate erythropoietin's versatile roles beyond erythropoiesis and its potential in tissue engineering and cancer.

June 20, 2026Frontiers in Bioengineering and BiotechnologyOpen Access

Erythropoietin in tissue engineering and beyond: a multifunctional macromolecule with emerging roles in organoids, immune modulation, and cancer research

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Authors

GSGaurav Sanghvi SBStefano Bellucci SBSuhas Ballal

Discussion

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Overview

Review explores erythropoietin's diverse therapeutic roles in tissue engineering, organoid development, and cancer biology, indicating its potential impact in regenerative medicine.

Key Points

This review aims to investigate erythropoietin's versatile roles beyond erythropoiesis and its potential in tissue engineering and cancer.
Explored EPO's biological properties and therapeutic potential in tissue repair and regeneration.
Analyzed innovative delivery methods including scaffold immobilization and hydrogel encapsulation.
Discussed EPO's role in organoid development and implications in cancer biology.
EPO demonstrated efficacy in regenerating multiple tissues, including bone and neural tissues.
Highlighted challenges such as maintaining EPO's bioactivity and controlled delivery.
Identified the dual role of EPO in tumor growth and immune modulation as critical for future research.

Cite This Study

Sanghvi et al. (2026) studied this question.

synapsesocial.com/papers/6a362d32db0793dc1a535acc https://doi.org/10.3389/fbioe.2026.1708887

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June 20, 2026Frontiers in Bioengineering and BiotechnologyOpen Access

Erythropoietin in tissue engineering and beyond: a multifunctional macromolecule with emerging roles in organoids, immune modulation, and cancer research

View Full Paper

Ask AI

Bookmark

Authors

GSGaurav Sanghvi SBStefano Bellucci SBSuhas Ballal

Discussion

Member takes

Overview

Review explores erythropoietin's diverse therapeutic roles in tissue engineering, organoid development, and cancer biology, indicating its potential impact in regenerative medicine.

Key Points

This review aims to investigate erythropoietin's versatile roles beyond erythropoiesis and its potential in tissue engineering and cancer.
Explored EPO's biological properties and therapeutic potential in tissue repair and regeneration.
Analyzed innovative delivery methods including scaffold immobilization and hydrogel encapsulation.
Discussed EPO's role in organoid development and implications in cancer biology.
EPO demonstrated efficacy in regenerating multiple tissues, including bone and neural tissues.
Highlighted challenges such as maintaining EPO's bioactivity and controlled delivery.
Identified the dual role of EPO in tumor growth and immune modulation as critical for future research.

Cite This Study

Sanghvi et al. (2026) studied this question.

synapsesocial.com/papers/6a362d32db0793dc1a535acc https://doi.org/10.3389/fbioe.2026.1708887

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