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This review aims to synthesize current evidence on how the microbiome affects epigenetic mechanisms in cancer.

The microbiome and its impact on the epigenome in cancer

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This review aims to synthesize current evidence on how the microbiome affects epigenetic mechanisms in cancer.
Reviewed literature on microbial metabolites like short-chain fatty acids and their effects on epigenetic marks.
Discussed interactions between the microbiome and epigenome in cancer progression and treatment responses.
Explored the concept of the 'oncobiome' and its potential as a therapeutic strategy.
Microbial metabolites can modify epigenetic marks, influencing tumor cell behavior.
Evidence suggests a link between disrupted microbiome and enhanced tumor progression and immune evasion.
Modulating the microbiome may offer new strategies for improving cancer therapy outcomes.

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Review reveals how microbiome impacts cancer risk and treatment through epigenetic regulation.

Kapoor et al. (2026) studied this question.

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