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June 20, 2026Journal of Cardiothoracic SurgeryOpen Access

Preoperative systemic immune-inflammation index as an incremental predictor of postoperative refractory hypoxemia in acute type a aortic dissection

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Authors

ZLZ W LiuYSYi ShenJZJuan Zou

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Overview

Retrospective cohort study evaluates preoperative biomarker in predicting postoperative hypoxemia, indicating its potential utility for better risk assessment.

Key Points

  • Evaluate the association between preoperative systemic immune-inflammation index and postoperative refractory hypoxemia.
  • Single-center retrospective cohort study analyzing 490 patients undergoing surgery for acute type A aortic dissection.
  • Preoperative systemic immune-inflammation index calculated from platelet, neutrophil, and lymphocyte counts.
  • Model discrimination and calibration evaluated using AUC and bootstrap resampling.
  • Postoperative refractory hypoxemia occurred in 158 of 490 patients (32.2%).
  • Preoperative SII was significantly higher in patients with hypoxemia, 1899.5 vs. 667.5 (P < 0.001).
  • Each doubling of SII was associated with an adjusted odds ratio of 2.80 (95% CI, 2.20-3.56; P < 0.001), improving predictive capability with an AUC increase from 0.750 to 0.846.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6a362de1db0793dc1a535eb6https://doi.org/10.1186/s13019-026-04435-9
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Can the Systemic Immune-inflammation Index be Used as a Predictive Marker for Short- and Mid-term Mortality in Aortic Dissection?2025
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  4. 4The Systemic Immune-Inflammation Index Predicts In-Hospital Mortality in Patients Who Underwent On-Pump Cardiac Surgery2024 · 7 citations
  5. 5Association of preoperative systemic immune-inflammation index and atherogenic index of plasma with early postoperative clinical outcomes in patients undergoing isolated elective coronary artery bypass grafting with cardiopulmonary bypass2026