Drug-related Sarcopenia and the Triad of Rehabilitation, Nutrition Support, and Oral Management

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Key Points

The aim is to explore the mechanisms of drug-related sarcopenia and propose integrated recovery strategies incorporating rehabilitation, nutrition support, and oral management.
Review key drug classes associated with sarcopenia and their clinical implications.
Propose strategies for pharmacotherapy optimization, focusing on dose reduction.
Integrate nutritional therapy and resistance exercises to enhance recovery outcomes.
Identified direct muscle toxicity of certain drug classes including statins and glucocorticoids.
Recommended a triad approach combining rehabilitation, nutritional support, and oral management for effective recovery.
Emphasized the need for systemic implementation of this triad in clinical settings.

Review explores drug-related sarcopenia mechanisms and recovery strategies in older adults, emphasizing an integrated approach.

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Yoshihiro Yoshimura (2026) studied this question.

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