Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 20, 2026Scientific ReportsOpen Access

Systematic review and meta-analysis of the effects of exercise in older adults with sarcopenia

View Full Paper
Ask AI
Bookmark
Share

Authors

MLMaria Clara Fagundes LucioRORaphael Gonçalves de OliveiraLALaura Isabel Martins de Almeida

Discussion

Loading...

Member takes

Overview

Randomized trial examines exercise effects on skeletal muscle mass and strength in older adults with sarcopenia, indicating exercise's critical role.

Key Points

  • The study aimed to assess how physical exercise affects muscle mass, strength, and performance in older adults with sarcopenia.
  • Conducted a systematic search across multiple databases up to May 26, 2025.
  • Included 72 randomized controlled trials assessing various exercise modalities.
  • Performed meta-analyses using standardized mean differences and GRADE to evaluate evidence quality.
  • Physical exercise improved skeletal muscle mass (small effect size), muscle strength, and physical performance (moderate effect size) compared to control.
  • Resistance exercise was significantly more effective than aerobic exercise for increasing skeletal muscle mass (large effect size).
  • The combination of exercise and nutritional supplementation enhanced muscle mass and strength more than either intervention alone.

Cite This Study

Lucio et al. (2026) studied this question.

synapsesocial.com/papers/6a362e62db0793dc1a536153https://doi.org/10.1038/s41598-026-55850-w
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The intervention effects of resistance exercise on sarcopenia in older adults: a systematic review and meta-analysis2026
  2. 2Effectiveness of home-based exercise interventions in the management of Sarcopenia in older adults: a systematic review of randomized controlled trials2026
  3. 3Exercise and Nutrition for Sarcopenia: A Systematic Review and Meta-Analysis with Subgroup Analysis by Population Characteristics2025 · 26 citations
  4. 4The effects of combined aerobic and resistance exercise on older adults with sarcopenia: a meta-analysis2026
  5. 5The Role of Resistance Exercises in Sarcopenia in Geriatric Population: A literature review2026