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June 20, 2026Folia MedicaOpen Access

Clinical value of causative pathogen identification in one-stage revision for periprosthetic joint infection

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Authors

GLGeorgi LukanovAPAtanas PanevLTLubomir Tzvetanov

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Overview

Randomized trial highlights improved outcomes in periprosthetic joint infections through pathogen identification and antibiotic guidance, indicating its clinical value.

Key Points

  • The aim is to emphasize the significance of recognizing the causative microorganism and its antibiotic profile for effective one-stage revision treatment of periprosthetic joint infection.
  • Conducted a one-stage revision total hip arthroplasty in 33 patients between October 2017 and July 2023.
  • Performed preoperative joint aspiration and intraoperative tissue sampling for microbiological analysis.
  • Followed patients postoperatively for an average of 33 months to assess outcomes.
  • Identified pathogens in 31 patients, with Staphylococcus epidermidis in 44.1% and Staphylococcus aureus in 14.7% of cases.
  • No recurrences of infection occurred during follow-up.
  • Mean Harris Hip Score improved significantly from 54.3 preoperatively to 72.3 postoperatively.

Cite This Study

Lukanov et al. (2026) studied this question.

synapsesocial.com/papers/6a362e62db0793dc1a5362cfhttps://doi.org/10.3897/folmed.68.e182189
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The incidence of deep prosthetic infections in a specialist orthopaedic hospital2006 · 520 citations
  2. 2Periprosthetic joint infection: current concepts and outlook2019 · 613 citations
  3. 3Comparison of surgical treatments for hip and knee periprosthetic joint infections using the desirability of outcome ranking in a prospective multicentre study2025 · 4 citations
  4. 4Risk Factors for Failure After 1-Stage Exchange Total Knee Arthroplasty in the Management of Periprosthetic Joint Infection2019 · 74 citations
  5. 5Clinical Outcomes After Revision Hip Arthroplasty due to Prosthetic Joint Infection—A Single-Center Study of 369 Hips at a High-Volume Center With a Minimum of One Year Follow-Up2023 · 17 citations