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Prospective analysis reveals increased gallstone risk in patients with PSC, suggesting genetic factors play a significant role.
Background and objective: Gallstone disease (GD) is common in primary sclerosing cholangitis (PSC), affecting up to 25% of patients (Said et al. J Hepatol 2008). The development of GD is linked to chronic cholestasism disturbances in bile acid homeostasis, and impaired gallbladder motility which [for full text, please go to the a.m. URL]
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Kruk et al. (2026) studied this question.
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