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June 20, 2026DiseasesOpen Access

Intramedullary Nailing Versus Modular Megaprosthesis in Pathological Humeral Fractures: A 10-Year Retrospective Comparative Study

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Authors

GRGiuseppe RovereFMFederica MessinaCMCesare Meschini

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Overview

Retrospective study compares functional outcomes in oncologic patients with humeral fractures, indicating tailored surgical choices.

Key Points

  • This study aims to compare the effectiveness of intramedullary nailing versus modular megaprosthesis for functional recovery in humeral fractures due to metastatic disease.
  • Retrospective observational study involving 48 patients with pathological humeral fractures from 2015 to 2025.
  • Patients were divided into intramedullary nailing (24) and modular megaprosthesis (22) groups.
  • Functional outcomes assessed using MSTS, QuickDASH, and WOSI scores over 10 years.
  • Intramedullary nailing showed significantly higher MSTS scores (78% vs. 63%, p < 0.001) at 1 month.
  • Early functional recovery was better with intramedullary nailing, but both techniques reached comparable outcomes by 2–3 years (p > 0.05).
  • Complication rates were similar, though periprosthetic infections occurred only in the megaprosthesis group (p = 0.28).

Cite This Study

Rovere et al. (2026) studied this question.

synapsesocial.com/papers/6a362f11db0793dc1a536a8dhttps://doi.org/10.3390/diseases14060218
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