]pyrene (BaP) - a prototypical polycyclic aromatic hydrocarbon (PAH) - induced metabolic perturbations at single-cell resolution in HepG2 cells. The uptake and clearance curve of intracellular BaP as well as the dynamic metabolic trajectory across exposure time were successfully resolved, initially characterizing the coupling relationship between exogenous exposure and endogenous metabolic status.
No takes yet. Share an insight, caveat, or question.
Zhang et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: