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This review aims to summarize the effectiveness, safety, and dosing of radioiodine therapy for hyperthyroidism.

Treating Hyperthyroidism With Radioiodine

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This review aims to summarize the effectiveness, safety, and dosing of radioiodine therapy for hyperthyroidism.
Reviewed studies from PubMed and Elicit, published from 2000 to 2025.
Included randomized controlled trials, cohort studies, and meta-analyses with at least 100 patients.
Smaller studies were also considered for dosing or special populations.
Radioiodine therapy achieved remission in 65.5%–87.7% of patients; relapse rates were 15% versus 52.7% after antithyroid drugs.
Increased risk of new or worsening ophthalmopathy was noted with radioiodine therapy.
Radioiodine was highly effective in pediatric patients, but older adults faced higher mortality risk.

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Review summarizes the effectiveness and safety of radioiodine therapy for hyperthyroidism, highlighting implications for treatment choices.

Park et al. (2026) studied this question.

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Review summarizes the effectiveness and safety of radioiodine therapy for hyperthyroidism, highlighting implications for treatment choices.