Dual-Mode pH-Programmable Enzymatic Hydrogel System for On-Demand Glucose Generation

Lillian Yeatman; Hannah Hutchinson; N. Ventura; Murdoch DeGray; Evgeny Katz; Oleh Smutok

doi:10.1039/d6sm00452k

January 1, 2026Soft Matter

Dual-Mode pH-Programmable Enzymatic Hydrogel System for On-Demand Glucose Generation

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Key Points

This research aims to explore the relationship between mass transport and enzymatic reaction kinetics in a dual-mode hydrogel system for glucose generation.
Developed a supramolecular enzymatic hydrogel using starch, chitosan, and Ca²⁺-crosslinked alginate.
Investigated coupling between mass transport and enzymatic reaction kinetics through experimental analysis.
Successfully demonstrated the hydrogel's ability to generate glucose on demand under varying pH conditions.
Observed improved enzymatic activity corresponding to optimized mass transport dynamics.

Implication

Investigates glucose generation using a dual-mode enzymatic hydrogel system, indicating effective mass transport coupling with enzymatic reactions.

Abstract

We report a supramolecular enzymatic composite hydrogel system based on starch, chitosan, and Ca²⁺-crosslinked alginate, designed to investigate the coupling between mass transport and enzymatic reaction kinetics in a soft...

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Cite This Study

Yeatman et al. (2026) studied this question.

synapsesocial.com/papers/6a3630f5db0793dc1a537f33 https://doi.org/10.1039/d6sm00452k

View Full Paper

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Dual-Mode pH-Programmable Enzymatic Hydrogel System for On-Demand Glucose Generation

Key Points

Implication

Abstract

Discussion

Cite This Study

Dual-Mode pH-Programmable Enzymatic Hydrogel System for On-Demand Glucose Generation

Key Points

Implication

Abstract

Discussion

Cite This Study

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