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This review aims to decode the mechanisms by which gut microbiota influences host health and explores therapeutic applications.

June 20, 2026EngineeringOpen Access

Gut Microbiota–Host Crosstalk: Decoding Mechanisms and Therapeutic Opportunities

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Review demonstrates gut microbiota's influence on host health through metabolic pathways, implying therapeutic opportunities.

This review aims to decode the mechanisms by which gut microbiota influences host health and explores therapeutic applications.
Detailed exploration of microbiota-host interactions.
Assessment of microbial metabolites, structural components, and extracellular vesicles.
Comparison of various pathways affecting immune response and metabolic processes.
Gut microbiota-derived metabolites regulate metabolic pathways and immune system functions.
Microbial structural components trigger inflammatory responses through pattern recognition receptors.
Microextracellular vesicles influence signal transduction and metabolic homeostasis.

Zhang et al. (2026) studied this question.

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