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June 20, 2026Journal of Medical Case Reports0 citationsOpen Access

Brain Metastatic Paraganglioma From Liver: Case Report and Literature Review

Brain metastatic paraganglioma from liver: a case report and review of the literature

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Authors

HZHaitao ZhangXQXiaolong QiaoZWZixuan Wang

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Overview

Case report shows brain metastasis from hepatic paraganglioma in a female patient, highlighting clinical insights.

Key Points

  • To present a rare case of brain metastatic paraganglioma originating from the liver and review its clinical features and treatment protocols.
  • Presented a case of a 52-year-old female with headache and prior hepatic paraganglioma diagnosis.
  • Conducted surgical resection and histopathological examination of brain tissue showing distinct mutations.
  • Reviewed related literature to enhance clinical understanding and diagnostic approaches.
  • Confirmed diagnosis of brain metastatic PGL with mutations in CD274, KMT2B, and SDHB genes.
  • Post-treatment showed no brain recurrence after chemotherapy with temozolomide as of June 2024.
  • Development of enlarged lymph nodes in thoracic and abdominal regions noted after initial treatment.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/6a363147db0793dc1a53843chttps://doi.org/10.1186/s13256-026-06213-6
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