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June 20, 2026Journal of Pediatric Ophthalmology & Strabismus

Ocular Microstructural Alterations in Children With Spina Bifida: An Optical Coherence Tomography Study

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Authors

GGGamze Ucan GunduzPediatrics and GeneticsSTSema Nizam TekcanBursa Uludağ Üni̇versi̇tesi̇DED ErdemSağlık Bilimleri Üniversitesi

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Overview

Cross-sectional study investigates retinal and choroidal alterations in children with spina bifida, suggesting implications for ocular health.

Key Points

  • This study aims to examine microstructural changes in the retina, choroid, and optic nerve in children with spina bifida.
  • Cross-sectional study of 38 children with spina bifida and 32 age- and sex-matched controls.
  • Optical coherence tomography was used to image the macula, choroid, and retinal nerve fiber layer.
  • Comprehensive ophthalmological examinations were conducted.
  • Axial length was significantly shorter in spina bifida patients (P = .025) and hyperopia was more prevalent (P < .001).
  • Outer nuclear layer was thicker in spina bifida patients (P = .019), while inner nuclear and outer plexiform layers were thinner (P = .038, P = .035).
  • Subfoveal and nasal choroidal thicknesses were greater in spina bifida patients (P = .012, P = .038).

Cite This Study

Gunduz et al. (2026) studied this question.

synapsesocial.com/papers/6a363172db0793dc1a5384f9https://doi.org/10.3928/01913913-20260417-01
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