What question did this study set out to answer?

The aim is to explore how Learning Health Systems (LHS) can be effectively implemented and scaled in complex health organizations.

June 20, 2026SSM - Health SystemsOpen Access

Scaling learning health systems in practice: From interdisciplinary science to system integration

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Commentary highlights operationalizing learning health systems in health organizations, indicating practical guidance for successful implementation.

The aim is to explore how Learning Health Systems (LHS) can be effectively implemented and scaled in complex health organizations.
Describes a phased journey of implementing LHS in a large health system.
Uses Trillium Health Partners as an example of real-world application.
Highlights the mobilization of scientific, operational, and relational assets into learning functions.
Early projects generated actionable insights and strengthened collaborative routines.
The approach informed system reorientation and improved governance.
Emerging conditions for normalizing learning as an operational model were identified.

Desveaux et al. (2026) studied this question.

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Commentary highlights operationalizing learning health systems in health organizations, indicating practical guidance for successful implementation.