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June 18, 2026OncogenesisOpen Access

Editorial Expression of Concern: Estrogen receptor β activation impairs mitochondrial oxidative metabolism and affects malignant mesothelioma cell growth in vitro and in vivo

A. G. Manente D. Valenti G. Pinton P. V. Jithesh A. Daga L Rossi S.G. Gray K. J. O’Byrne D.A. Fennell R. A. Vacca S. Nilsson L. Mutti L. Moro

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Key Points

This editorial expresses concern regarding the effects of estrogen receptor β activation on mitochondrial function and cancer cell growth.
Focused on in vitro and in vivo evaluations of malignant mesothelioma cells.
Assessment of mitochondrial metabolism and cell proliferation in response to estrogen receptor β activation.
Estrogen receptor β activation leads to impaired mitochondrial oxidative metabolism.
It negatively affects the growth of malignant mesothelioma cells in both in vitro and in vivo models.

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Implication

Editorial Expression of Concern highlights impaired cell growth in malignant mesothelioma associated with estrogen receptor β activation.

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Cite This Study

Manente et al. (2026) studied this question.

synapsesocial.com/papers/6a363224db0793dc1a538cff https://doi.org/10.1038/s41389-026-00639-9

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