Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
June 20, 2026Journal of the International Association of Providers of AIDS Care (JIAPAC)Open Access

MASLD in PLWH on ART: Predominance of Metabolic Risk Factors and Insights From Novel Biomarkers—A Cross-Sectional Study in Wrocław, Poland

View Full Paper
Ask AI
Bookmark
Share

Authors

MBMichał BiałyWroclaw Medical UniversityMIMałgorzata InglotMarche Polytechnic University

Discussion

Loading...

Member takes

Overview

Cross-sectional study assesses metabolic factors influencing MASLD in PLWH on ART, suggesting implications for risk evaluation.

Key Points

  • This research aims to evaluate the prevalence of metabolic risk factors associated with MASLD in people living with HIV on antiretroviral therapy.
  • Conducted a cross-sectional study with 93 participants from an outpatient clinic in Poland.
  • Utilized clinical assessments, metabolic data, and novel biomarkers such as irisin and leptin.
  • Applied noninvasive formulas to evaluate MASLD risk biochemically.
  • No significant differences in MASLD-related scores across various antiretroviral therapy regimens.
  • Weak correlations were observed between CD4 count and NAFLD-LFS (R < .3) and ART duration with non-HDL-C (R = −.22).
  • Leptin displayed strong correlations with HSI (R = .56) and BMI (R = .53), indicating its potential role in assessing MASLD risk.

Cite This Study

Biały et al. (2026) studied this question.

synapsesocial.com/papers/6a363224db0793dc1a538dfdhttps://doi.org/10.1177/23259582261436955
View Full Paper
Ask AI
Bookmark
Share