Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 20, 2026American Journal of Reproductive ImmunologyOpen Access

Genital Immune Correlates of Seroprevalent and Seroincident Herpes Simplex Type 2 Infection Among Women Who Sell Sex in Nairobi, Kenya

View Full Paper
Ask AI
Bookmark
Share

Authors

SUSuji UdayakumarJPJames PollockEIErastus Irungu

Discussion

Loading...

Member takes

Overview

Randomized trial examines immune correlates of herpes simplex type 2 in women selling sex, suggesting limited HIV acquisition risks.

Key Points

  • This research aims to explore the relationship between herpes simplex virus type 2 and genital immune factors among women who sell sex.
  • Nested within the Maisha Fiti cohort studying women in Nairobi, Kenya.
  • HSV-2 serostatus assessed via Kalon HSV-2 IgG assay.
  • Logistic and linear regression analyses used to assess associations with immune factors.
  • Among 731 participants, 414 (57%) were HSV-2 seropositive, with significant age differences.
  • Seroincidence rate was 10.7 per 100 person-years; linked to older age, more clients, and bacterial vaginosis.
  • No significant immune predictors for HSV-2 acquisition after adjusting for Nugent score.

Cite This Study

Udayakumar et al. (2026) studied this question.

synapsesocial.com/papers/6a3632d2db0793dc1a5394b2https://doi.org/10.1111/aji.70273
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Sexual Violence, Genital Cytokines, and Colposcopy Findings: A Cross-Sectional Study of Women Engaged in Sex Work in Mombasa, Kenya2024 · 1 citations
  2. 2Epidemiological Patterns of Genital Ulcer Disease and Human Immunodeficiency Virus Among Public Clinic Attendees in Mthatha, Eastern Cape, South Africa2025 · 1 citations
  3. 3SEROPREVALENCE OF HERPES SIMPLEX VIRUS INFECTION TYPE 1 AND 2 IN A POPULATION OF HIV-POSITIVE AND HIV-NEGATIVE INDIVIDUALS IN A TERTIARY CARE HOSPITAL2024
  4. 4High prevalence of herpes simplex virus (HSV)- type 2 co-infection among HIV-positive women in Ukraine, but no increased HIV mother-to-child transmission risk2016 · 15 citations
  5. 5Seroprevalence of herpes simplex virus type 2 in multiple sclerosis2006 · 18 citations