Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 20, 2026BMC Cardiovascular DisordersOpen Access

Prognostic value of controlling nutritional status score (CONUT) and prognostic nutritional index (PNI) in patients with peripheral artery disease: an evidence-based analysis

View Full Paper
Ask AI
Bookmark
Share

Authors

YHY HeXHXiaoci HeMLMeng Liu

Discussion

Loading...

Member takes

Overview

Meta-analysis evaluates CONUT and PNI's prognostic value in peripheral artery disease, indicating their importance in identifying high-risk patients.

Key Points

  • The aim is to evaluate the prognostic value of CONUT and PNI in patients with peripheral artery disease (PAD).
  • Conducted a meta-analysis including 15 cohort studies with 6,830 PAD patients.
  • Extracted data on mortality, major adverse cardiovascular events, amputation, and ulcer healing.
  • Synthesized data using odds ratios and performed sensitivity analysis for stability assessments.
  • Higher CONUT scores linked to increased mortality (HR: 1.34; 95% CI: 1.21–1.49) and amputation risk (OR: 1.20; 95% CI: 1.10–1.32).
  • Higher PNI associated with reduced mortality (HR: 0.95; 95% CI: 0.92–0.97) and amputation risk (OR: 0.91; 95% CI: 0.87–0.95).
  • No significant association found between CONUT and major adverse cardiovascular events or poor ulcer healing.

Cite This Study

He et al. (2026) studied this question.

synapsesocial.com/papers/6a363326db0793dc1a539847https://doi.org/10.1186/s12872-026-06139-3
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prognostic Significance of Malnutrition Indices in ST-Elevation Myocardial Infarction: A Comparative Analysis of CONUT and PNI Scores After Primary PCI2026 · 1 citations
  2. 2Prognostic Potential of the Controlling Nutritional Status (CONUT) Score in Predicting All-Cause Mortality and Major Adverse Cardiovascular Events in Patients With Coronary Artery Disease: A Meta-Analysis2022 · 55 citations
  3. 3Association of nutritional status indices with clinical outcomes in acute pancreatitis2025
  4. 4Association of prognostic nutritional index with long-term mortality in patients receiving percutaneous coronary intervention for acute coronary syndrome: a meta-analysis2023 · 25 citations
  5. 5Association of prognostic nutritional index with peripheral artery disease in US adults: a cross-sectional study2024 · 9 citations