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This review aims to explore the evolution of surgical management for cancer of the esophagogastric junction, emphasizing anatomical considerations.

June 20, 2026Gut MedicineOpen Access

Anatomical Understanding and Evolution of Surgical Treatment for Cancer of the Esophagogastric Junction: From Anatomical Controversies to Precision Surgery

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Review highlights changes in surgical strategies for esophagogastric junction cancer, suggesting tailored approaches for improved outcomes.

This review aims to explore the evolution of surgical management for cancer of the esophagogastric junction, emphasizing anatomical considerations.
Review of recent literature on surgical techniques for esophagogastric junction cancer
Analysis of historical and current surgical strategies
Synthesis of prospective data on lymph node dissection and gastrectomy practices
Shift from tumor epicenter to length of esophageal invasion for surgical decision-making
Invasion-length thresholds of 2.0 and 4.0 cm determine lymph node dissection extent
Transition from routine total gastrectomy to proximal gastrectomy with advanced reconstruction techniques

Sun et al. (2026) studied this question.

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Review highlights changes in surgical strategies for esophagogastric junction cancer, suggesting tailored approaches for improved outcomes.