Higher baseline mean left ventricular wall thickness was associated with greater 6-month improvement in LVEF after AF ablation (1.72% per 1 mm; 95% CI 0.83-2.61; P<0.001).
Cohort (n=342)
Does baseline left ventricular wall thickness and its regional heterogeneity predict recovery of LVEF after AF ablation in patients with systolic dysfunction?
Baseline left ventricular wall thickness and its regional heterogeneity assessed by MDCT independently predict post-ablation functional recovery in patients with AF and systolic dysfunction.
Mean Difference: 1.72 (95% CI 0.83–2.61)
valor p: p=<0.001
Background Left ventricular functional recovery after atrial fibrillation (AF) ablation varies widely in patients with systolic dysfunction. Objective To evaluate whether baseline left ventricular wall thickness (LVWT) and its regional heterogeneity predict recovery of left ventricular ejection fraction (LVEF) after AF ablation. Methods Of 5,535 consecutive patients undergoing first-time AF ablation (2012−2024), 342 with baseline LVEF 1.2 mm) had the highest incidence of heart failure hospitalization or cardiovascular death. Conclusion Baseline LVWT and its regional heterogeneity were independently associated with post-ablation functional recovery in patients with baseline LVEF <50%. Preprocedural LVWT assessment may help estimate myocardial reserve and expected functional recovery after AF ablation.
Okada et al. (Mon,) conducted a cohort in Atrial fibrillation with systolic dysfunction (n=342). Baseline left ventricular wall thickness (LVWT) was evaluated on 6-month change in LVEF (ΔLVEF) on echocardiography (1.72% per 1 mm, 95% CI 0.83-2.61, p=<0.001). Higher baseline mean left ventricular wall thickness was associated with greater 6-month improvement in LVEF after AF ablation (1.72% per 1 mm; 95% CI 0.83-2.61; P<0.001).