The prevalence of carotid artery stenosis was 25.4% in patients with coronary artery disease compared to 7.0% in those without, and increased significantly with the extent of CAD (P<0.0001).
Cross-Sectional (n=632)
What is the prevalence of carotid artery stenosis in Japanese patients undergoing coronary angiography for suspected coronary artery disease?
The prevalence of carotid artery stenosis is high among Japanese patients with coronary artery disease and correlates strongly with the extent of CAD, supporting routine screening in older patients with multivessel disease.
Absolute Event Rate: 25.4% vs 7%
p-value: p=<0.0001
BACKGROUND AND PURPOSE: Prevalence of carotid artery stenosis in patients with coronary artery disease (CAD) is unknown in Japanese population. METHODS: The study populations consisted of 632 consecutive patients who underwent coronary angiography because of suspicion of CAD. All patients underwent carotid ultrasonography to screen carotid artery stenosis before coronary angiography. We defined echographic carotid stenosis as area stenosis of >50% or peak systolic velocity of >200 cm/s. RESULTS: Echographic carotid stenosis was observed in 124 patients (19.6%). Coronary angiography revealed 433 patients had CAD. Prevalence of echographic carotid artery stenosis was 14 of 199 (7.0%), 18 of 124 (14.5%), 28 of 131 (21.4%), and 64 of 178 (36.0%) in patients with 0-, 1-, 2-, and 3-vessel CAD, respectively (P<0.0001). The prevalence rate with carotid stenosis and CAD was 25.4%. Multivariate stepwise logistic regression analysis showed that age and the extent of CAD were independently related to the presence of carotid stenosis (P=0.0002 and <0.0001, respectively). CONCLUSIONS: Prevalence of carotid stenosis in patients with CAD is high in Japan as well as in Western countries. Screening of carotid artery stenosis is recommended especially in older patients with multivessel CAD.
Tanimoto et al. (Fri,) conducted a cross-sectional in Coronary artery disease (n=632). Coronary artery disease vs. No coronary artery disease (0-vessel CAD) was evaluated on Echographic carotid artery stenosis (area stenosis >50% or peak systolic velocity >200 cm/s) (p=<0.0001). The prevalence of carotid artery stenosis was 25.4% in patients with coronary artery disease compared to 7.0% in those without, and increased significantly with the extent of CAD (P<0.0001).