Majorbio Cloud: An integrated platform for single‐omics and integrated multi‐omics analysis of microbiome and metabolome

Advances in sequencing and mass spectrometry have propelled life sciences into the multi-omics era. Metabolomics and microbiomics are widely applied across various research fields, yet massive data analysis faces challenges like limited tool functionality and high technical barriers. The Majorbio Cloud Platform addresses these pain points by establishing four integrated workflows: Untargeted metabolomics, targeted metabolomics, microbiomics, and microbiome-metabolome integrated analysis, enabling one-stop analysis from single-omics to multi-omics correlation. In a real gut microbiome–metabolome case study, the platform pinpointed core differential microbes and characteristic metabolites, and further annotated functional pathways underlying host phenotypic divergence, demonstrating its reliability for mining biological mechanisms. The platform caters to both novice and experienced researchers with dual-parameter modes (default/customizable), multi-user collaboration, standardized pipelines, advanced analytical tools, and one-click color customization. By simplifying complex analytical procedures and reducing reliance on specialized programming skills, it offers a standardized, reproducible solution for multi-omics data analysis in related fields.