Calorimetric study examines solvation energy in mixed ethanol-DMSO solvents, indicating significant solute-solvent interaction effects.
In this study, the heat effects of dissolution of pyridine (Py) in mixed solvents ethanol–dimethyl sulfoxide (EtOH–DMSO, χDMSO = 0–1 mole fraction, 25°C) were determined using a calorimetric method. The experimental and calculated standard enthalpies of solvation of the heterocycle (ΔsolvH0(Py)) in the solvents studied were found. The calculated values of ΔsolvH0(Py) were determined by quantum chemical modeling using the continuum solvation model. The contributions of universal and specific types of solute-solvent interactions to the change in the solvation energy of Py with a change in the solvent composition EtOH → (EtOH–DMSO) were analyzed.
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Kuz’mina et al. (2026) studied this question.
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