Synthesis and solubility of 1-[2-methyl-1-(4-methylphenyl)-5-phenyl-1h-pyrrol-3-yl]ethanol in organic solvents

Q: What type of study is this?

This is a Quantitative Study study (also classified as: Experimental Study).

R. R. Kostiuk; Yuriy I. Horak; Мыкола Д. Обушак; N. I. Tyshchenko; I.B. Sobechko

doi:10.23939/ctas2025.01.017

June 1, 2025Chemistry Technology and Application of Substances

Synthesis and solubility of 1-[2-methyl-1-(4-methylphenyl)-5-phenyl-1h-pyrrol-3-yl]ethanol in organic solvents

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Key Points

The study found specific enthalpy and entropy values for the dissolution of the compound in various solvents, revealing their behavior at different temperatures.
Measured melting point and thermodynamic parameters were established using differential thermal analysis, showing significant melting characteristics.
The calculations for enthalpy and entropy were adjusted to 298.15 K, providing a standard reference for understanding the compound's solubility.
Thermodynamic mixing parameters were evaluated across several organic solvents, highlighting the compound's compatibility with these solvents.

Implication

Research reveals the temperature dependence of solubility and thermodynamic parameters in organic solvents, indicating potential applications.

Abstract

The temperature dependence of the solubility of 1-[2-methyl-1-(4-methylphenyl)-5-phenyl- 1H-pyrrol-3-yl]ethanone in methyl acetate, ethyl acetate, acetonitrile, propan-1-ol and propan-2-ol has been investigated. The enthalpy and entropy of dissolution were calculated. The thermodynamic parameters of the melting process and the melting point were determined based on the results of differential thermal analysis. The enthalpy and entropy of melting were recalculated to 298.15 K. The enthalpy and entropy of mixing 1-[2-methyl-1-(4-methylphenyl)-5- phenyl-1H-pyrrol-3-yl]ethanone with methyl acetate, ethyl acetate, acetonitrile, propan-1-ol, and propan-2-ol were calculated.

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Cite This Study

Kostiuk et al. (2025) studied this question.

synapsesocial.com/papers/68d44c5531b076d99fa56222 https://doi.org/10.23939/ctas2025.01.017

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Synthesis and solubility of 1-[2-methyl-1-(4-methylphenyl)-5-phenyl-1h-pyrrol-3-yl]ethanol in organic solvents

Key Points

Implication

Abstract

Discussion

Cite This Study

Synthesis and solubility of 1-[2-methyl-1-(4-methylphenyl)-5-phenyl-1h-pyrrol-3-yl]ethanol in organic solvents

Key Points

Implication

Abstract

Discussion

Cite This Study

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