This experimental study demonstrates how methylation of circKPNA2 drives colorectal cancer cell behavior, suggesting therapeutic potential.
A) methylation, which in turn affects CRC cell proliferation, migration, and invasion. These results deepen our understanding of CRC biology and underscore the potential of targeting circKPNA2 as both a therapeutic target and a diagnostic biomarker to improve CRC diagnosis and treatment.
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Tian et al. (2026) studied this question.
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