What question did this study set out to answer?

The aim is to identify preoperative predictors of benign histology in small renal masses to refine treatment selection.

Predictors of benign histology in clinical T1a small renal masses: A large multicenter cohort study

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Retrospective multicenter study identifies predictors of benign tumors in small renal masses, suggesting less invasive treatment options.

The aim is to identify preoperative predictors of benign histology in small renal masses to refine treatment selection.
Performed a retrospective multicenter cohort study at eight centers in South Korea from 1990 to 2023.
Compared clinicodemographic, laboratory, and radiologic variables between benign and malignant tumors.
Used multivariable logistic regression to identify independent predictors of benign pathology.
Among 5,713 renal masses, 289 (5.1%) were benign.
Benign tumors were more common in females (58.8% vs. 28.2%, p<0.001) and had lower BMI (23.60 kg/m² vs. 24.80 kg/m², p<0.001).
Independent predictors for benign histology included female sex (OR 3.126, p<0.001), tumor size ≤2 cm (OR 2.335, p<0.001), lower BMI (OR 0.910 per kg/m², p<0.001), and higher eGFR (OR 1.023 per mL/min/1.73m², p<0.001).

Lee et al. (2026) studied this question.

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View Full Paper

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Authors

Retrospective multicenter study identifies predictors of benign tumors in small renal masses, suggesting less invasive treatment options.

The aim is to identify preoperative predictors of benign histology in small renal masses to refine treatment selection.
Performed a retrospective multicenter cohort study at eight centers in South Korea from 1990 to 2023.
Compared clinicodemographic, laboratory, and radiologic variables between benign and malignant tumors.
Used multivariable logistic regression to identify independent predictors of benign pathology.
Among 5,713 renal masses, 289 (5.1%) were benign.
Benign tumors were more common in females (58.8% vs. 28.2%, p<0.001) and had lower BMI (23.60 kg/m² vs. 24.80 kg/m², p<0.001).
Independent predictors for benign histology included female sex (OR 3.126, p<0.001), tumor size ≤2 cm (OR 2.335, p<0.001), lower BMI (OR 0.910 per kg/m², p<0.001), and higher eGFR (OR 1.023 per mL/min/1.73m², p<0.001).

Lee et al. (2026) studied this question.

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