What question did this study set out to answer?

This report aims to highlight the risk of overwhelming post-splenectomy infection (OPSI) years after splenectomy for immune thrombocytopenic purpura.

June 21, 2026CureusOpen Access

Fatal Delayed-Onset Overwhelming Post-splenectomy Infection 26 Years After Splenectomy for Immune Thrombocytopenic Purpura

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Authors

DRDavid RamzySt. Joseph’s University Medical Center RIRouba Isshak KVKatrina Villegas

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Implication

Case report reveals fatal overwhelming post-splenectomy infection in a patient 26 years post-surgery, highlighting critical risks and prevention strategies.

Key Points

This report aims to highlight the risk of overwhelming post-splenectomy infection (OPSI) years after splenectomy for immune thrombocytopenic purpura.
Case analysis of a 36-year-old female 26 years post-splenectomy.
Monitoring of clinical symptoms and diagnostic tests upon hospital admission.
Aggressive management protocol for septic shock and related complications.
Confirmed Streptococcus pneumoniae bacteremia with additional non-COVID-19 pathogens.
Patient progressed to septic shock with severe complications, including acute respiratory failure.
Died within 48 hours despite aggressive treatment efforts.

Cite This Study

Ramzy et al. (2026) studied this question.

synapsesocial.com/papers/6a37800c24f042ddf4c5a339 https://doi.org/10.7759/cureus.111184

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Implication

Case report reveals fatal overwhelming post-splenectomy infection in a patient 26 years post-surgery, highlighting critical risks and prevention strategies.

Fatal Delayed-Onset Overwhelming Post-splenectomy Infection 26 Years After Splenectomy for Immune Thrombocytopenic Purpura

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Member takes

Implication

Key Points

Cite This Study

Fatal Delayed-Onset Overwhelming Post-splenectomy Infection 26 Years After Splenectomy for Immune Thrombocytopenic Purpura

Discussion

Member takes

Implication

Key Points

Cite This Study

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