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The aim is to create a growth model for hip morphology from childhood to young adulthood, differentiating by sex.

June 21, 2026Osteoarthritis ImagingOpen Access

Hip Morphology Development From Childhood to Young Adulthood

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Randomized trial develops a growth model of hip morphology in children and adolescents, suggesting implications for hip OA prevention.

The aim is to create a growth model for hip morphology from childhood to young adulthood, differentiating by sex.
Utilized data from the Generation R Study, a cohort examined at ages 6, 9, 13, and 18 years.
Included participants with high-resolution AP DXA scans of the right hip across three or four timepoints (N=1610).
Analyzed hip shape using a statistical shape model and linear mixed-effects models to observe longitudinal changes related to sex and age.
Analyzed 5141 observations with six shape modes explaining 85% of variation in hip morphology.
Shape modes 1-3 demonstrated significant age-related changes, linked to femoral head calcification and size compared to the acetabulum.
Linear models showed improvement when including the interaction of sex assigned at birth.

Hendriks et al. (2026) studied this question.

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