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Frequency and Genetic Characterization of Echinococcus granulosus in Paraffin‐Embedded Human Tissue Samples From the Northwest of Iran, West Azarbayjan

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Cross-sectional study investigates molecular characteristics of Echinococcus granulosus in patients, highlighting health impacts.

The study aimed to explore the epidemiological and molecular characteristics of Echinococcus granulosus within human tissue samples in northwest Iran.
Cross-sectional analysis of 295 hydatid cyst patients from surgeries between 2010 and 2021.
DNA extracted from 74 formalin-fixed paraffin-embedded cyst samples using PCR targeting cox1 and nad1 genes.
Mitochondrial gene sequences were analyzed for haplotypic variation using BioEdit and BLAST software.
CE frequency was highest in patients aged 20-30 years, with significant prevalence among villagers and low-educated individuals.
Liver and lung were the most common cyst locations, with 17.6% and 13.6% respectively.
All samples analyzed resulted in the G1 genotype, indicating no haplotypic variation.

Boustani et al. (2026) studied this question.

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