Key result
With proper technical refinements and strict postoperative blood pressure control, the Ross procedure may be the best operation to treat young adults with non-repairable aortic regurgitation.
Why the study?
The role of the Ross procedure in non-repairable aortic regurgitation remains debated due to historical reports of increased pulmonary autograft dilatation and reintervention risk.
Does the Ross procedure with technical refinements improve outcomes and prevent autograft dilatation in young and middle-aged adults with non-repairable aortic regurgitation?
Does the Ross procedure with technical refinements improve outcomes and prevent autograft dilatation in young and middle-aged adults with non-repairable aortic regurgitation?
Answers are grounded in this paper and cite their sources.
Despite current guidelines recommending against it, the Ross procedure may still be the optimal surgical option for young adults with non-repairable aortic regurgitation when specific technical modifications are employed to prevent autograft dilatation.
The Ross procedure is the best operation to treat aortic stenosis (AS) in young and middle-aged adults. However, its role in non-repairable aortic regurgitation (AR) remains debated since many historical series have reported an increased risk of pulmonary autograft dilatation and subsequent need for reintervention in these patients. Some have attributed these findings to an unrecognized and poorly characterized inherited genetic defect that prevents adaptive remodelling of the pulmonary autograft. Herein, we review the contemporary evidence surrounding the use of the Ross procedure in young adults with AR and put forth the argument that with proper technical refinements, the Ross procedure may still be the best operation to treat these patients. We believe that by tailoring the operation to the patient's anatomy and ensuring strict postoperative blood pressure control, one can achieve excellent results with the Ross procedure, including in this challenging patient population.
No takes yet. Share an insight, caveat, or question.
Mazine et al. (2021) conducted a review in Aortic regurgitation. Ross procedure was evaluated. With proper technical refinements and strict postoperative blood pressure control, the Ross procedure may be the best operation to treat young adults with non-repairable aortic regurgitation.
Synapse has enriched 10 related papers. Consider them for comparative context: