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June 22, 2026BMC SurgeryOpen Access

Analysis of predictive factors and development of a nomogram for complicated acute appendicitis in adults

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Authors

JYJin YuFirst People’s Hospital of JingmenSLShixing LiFirst People’s Hospital of JingmenYMYulin MaFirst People’s Hospital of Jingmen

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Implication

Randomized trial analyzes predictive factors and develops a nomogram for complicated acute appendicitis, indicating enhanced prediction accuracy.

Key Points

  • This study aimed to analyze the predictive factors for complicated acute appendicitis and establish a nomogram for risk assessment.
  • Included patients who underwent appendectomy from January 2023 to October 2025.
  • Performed univariate and multivariate analyses to identify predictive factors.
  • Constructed a nomogram prediction model and evaluated performance using ROC, calibration curve, and decision curve analysis.
  • The incidence of complicated acute appendicitis was 25.24%.
  • Identified independent predictors: age (OR 3.697), body temperature (OR 3.235), neutrophil percentage (OR 2.317), C-reactive protein (OR 12.434), appendix diameter (OR 30.731), and appendiceal fecalith (OR 6.968).
  • The ROC curve area was 0.959, with a sensitivity of 87.3% and specificity of 90.3%.

Cite This Study

Yu et al. (2026) studied this question.

synapsesocial.com/papers/6a38d0a8da1bad9caca30a8fhttps://doi.org/10.1186/s12893-026-03965-2
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Predictive model for identification of gangrenous or perforated appendicitis in adults: a multicenter retrospective study2024 · 12 citations
  2. 2Emergency appendicectomy in Australia: findings from a multicentre, prospective study2017 · 36 citations
  3. 3The Diagnostic Value of D-dimer, Procalcitonin and CRP in Acute Appendicitis2012 · 87 citations
  4. 4Clinical prediction of complicated appendicitis: A case-control study utilizing logistic regression2020 · 24 citations