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June 22, 2026Open Access

Parkinson's disease in the Era of Precision Medicine: From Early Detection to Disease Modification

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Authors

DPDhruvi PatelSSSatyajit SahooSPSohan Patel

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Overview

Randomized trial explores disease-modifying therapies in Parkinson's disease, highlighting new management options.

Key Points

  • To investigate Parkinson’s disease as a multifaceted condition influenced by genetic and environmental factors and explore emerging therapies.
  • Evaluation of subtypes of Parkinson's disease based on genetic and environmental factors.
  • Assessment of early symptoms such as loss of smell and constipation before motor issues.
  • Investigation of new therapies including vaccines, antibodies, and targeted medication delivery.
  • Identification of misfolding of alpha-synuclein as a core mechanism damaging brain cells.
  • Emerging therapies show promise in targeting genetic forms like GBA and LRRK2.
  • Increased understanding of neurotransmitter disruptions contributing to symptom variability.

Cite This Study

Patel et al. (2026) studied this question.

synapsesocial.com/papers/6a38d17ada1bad9caca3111ehttps://doi.org/10.5281/zenodo.20770760
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