Synthesis and Identification of New imidazolidine-4-one Derivatives and Study of their Biological Activity as Anti-bacteria, Fungi and oxidant.

In this study, a new heterocyclic compound called imidazolidine-4-one derivatives was synthesized by first reacting thiosemicarbazide with carbon disulfide to create gate thiadiazole compound (A). This compound then interacted with 2-hydroxy benzoic acid to create azo compound (B), which then interacted with substituted phenyl amines to create Schiff base (S1-S8), which then reacted with 2-amino acetic acid to produce imidazolin-4-one derivatives. These compounds are all characterized by 1HMNR, 13C-NMR, and Fourier-transform infrared spectroscopy (FT-IR). Next, we examine the biological characteristics of all heterocyclic derivatives to protect against two types of bacteria, one kind of fungus, and antioxidants. The synthesized compounds' antifungal efficacy using the diffusion method . Imidazolin-4-one derivatives were found to be more effective against Candida in an antifungal. The reducing abilities of the investigated compounds were measured. This study provides key molecular insights that can be utilized to assess the antibacterial and antifungal activities of the Imidazolin-4-one ring and enhance its antioxidant properties