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Highlights potential arrhythmia mechanism in alcoholic cardiomyopathy; leaves open clinical translation from this animal model.
Chronotopography of atrial subepicardium depolarization has been studied in a rat model of alcoholic cardiomyopathy. Formation of independent sources of initial atrial activity has been detected in the right and left atria. These sources induced the formation of several depolarization fronts that propagated autonomously, and this can be regarded as the cause of atrial arrhythmia.
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Смирнова et al. (2018) studied this question.
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